Serotyping Dichelobacter nodosus with PCR-SSCP

nodosus . associated with virulence in Dichelobacter

Within-Flock Population Dynamics of Dichelobacter nodosus

Footrot causes 70-90% of lameness in sheep in Great Britain. With approximately 5% of 18 million adult sheep lame at any one time, it costs the UK sheep industry £24-84 million per year. The Gram-negative anaerobe Dichelobacter nodosus is the causative agent, with disease severity influenced by bacterial load, virulence, and climate. The aim of the current study was to characterize strains of D...

Kars Yöresi Koyunlarında Piyeten Olgularından Dichelobacter nodosus İzolasyonu ve PCR İle İdentifikasyonu

In this study it was aimed to isolation and identification by PCR of specific agent from ovine footrot in Kars district and thus determination of prevalence of disease. To this end, 8,970 sheep belong to 10 different flocks were examined clinically, and in 1532 of these (17.07%) were found lameness for various reasons. Out of 247 (2.75%) of these cases were evaluated to be footrot suspect clini...

Experimental infection of cattle with ovine Dichelobacter nodosus isolates

BACKGROUND Dichelobacter nodosus is the main causative agent of ovine footrot, and there are strong indications that the bacterium can be transferred to cattle grazing on the same pasture as sheep. The aim of this study was to investigate if benign and virulent D. nodosus strains isolated from sheep can be transferred to the interdigital skin of cattle under experimental conditions. Further, we...

Twitching motility is essential for virulence in Dichelobacter nodosus.

Type IV fimbriae are essential virulence factors of Dichelobacter nodosus, the principal causative agent of ovine foot rot. The fimA fimbrial subunit gene is required for virulence, but fimA mutants exhibit several phenotypic changes and it is not certain if the effects on virulence result from the loss of type IV fimbria-mediated twitching motility, cell adherence, or reduced protease secretio...